abstract：:Rabbit retinas were maintained in a physiological state in vitro and exposed to 0.5-h pulses of labeled leucine. Protein synthesis was determined from incorporation of the label, and degradation from its subsequent release. The retinas were treated as test-control pairs. The control retina remained in darkness while t...

journal_title：Journal of neurochemistry

authors： Ames A 3rd,Parks JM,Nesbett FB

更新日期：1980-07-01 00:00:00

abstract：:Vinblastine causes alterations in the subcellular distribution of certain proteins synthesized by telencephalon slices. Proteins in various subcellular fractions were separated according to their molecular weight by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, and radioactive proteins were determined by ...

journal_title：Journal of neurochemistry

authors： White FP

更新日期：1980-07-01 00:00:00

abstract：:The recycling of methionine via homocysteine was measured in vivo in brain. After constant intravenous infusions (5 h) of both [3H-methyl]methionine and [35S]methionine into rats, the ratios of [3H-methyl]methionine to [35S]methionine in liver, brain, and plasma were determined. Similar experiments were performed in r...

journal_title：Journal of neurochemistry

authors： Spector R,Coakley G,Blakely R

更新日期：1980-01-01 00:00:00

abstract：:Accumulations of the neuropeptides substance P (SP), somatostatin (ST), and vasoactive intestinal polypeptide (VIP) proximal to a crush in the cervical vagus nerve of the rat have been measured using sensitive radioimmunoassays. Each of the peptides was rapidly transport towards the peripheral terminals of vagal affer...

journal_title：Journal of neurochemistry

authors： Gilbert RF,Emson PC,Fahrenkrug J,Lee CM,Penman E,Wass J

更新日期：1980-01-01 00:00:00

abstract：:Five-day-old rats subjected to prolonged asphyxia at 37 degrees C show a slower rate of synthesis of 5-HT as measured by the accumulation of the amine after inhibition of monoamine oxidase. During recovery from asphyxia 5-HT synthesis is markedly stimulated when measured over a 50 or 90 min period. No change in 5-HT s...

journal_title：Journal of neurochemistry

authors： Tricklebank MD,Pickard FJ,Dobbing J

更新日期：1976-11-01 00:00:00

abstract：:Rapid axonal transport of proteins in retinal ganglion cells of the rabbit was studied following intraocular injections of labelled amino acids. Approximately 10% of the transported radioactivity was found in the supernatant following homogenization and high-speed centrifugation of the nerve terminal region. Relativel...

journal_title：Journal of neurochemistry

authors： Karlsson JO

更新日期：1976-11-01 00:00:00

abstract：:The lipid composition of the brain, including myelin, was studied in detail in two cases with a variant form of metachromatic leukodystrophy (multiple sulphatase deficiency type). In the white matter, the sulphatide concentration was 3-4 times higher than the normal level in both cases. There was a significant accumul...

journal_title：Journal of neurochemistry

authors： Eto Y,Meier C,Herschkowitz NN

更新日期：1976-11-01 00:00:00

abstract：:The translocation of intravenously administered tritiated 3-O-methyl-D-glucopyranose (3-OMG) into brain has been studied in an intact nephrectomized rat preparation by infusing a series of hexoses into one internal carotid artery. 3-OMG rapidly penetrated into brain with peak concentrations, attained 5-8 min after inj...

journal_title：Journal of neurochemistry

authors： Bidder TG

更新日期：1968-08-01 00:00:00

abstract：:Choline acetyltransferase (acetyl-CoA: choline O-acetyltransferase, I.U.B. 2.3.1.6) activity and total protein content in visual and extra-visual areas were compared in normal Long-Evans rats and in rats subjected to complete light-deprivation for 21 days from birth. The enzyme activity and the protein content in the ...

journal_title：Journal of neurochemistry

authors： Maletta GJ,Timiras PS

更新日期：1968-08-01 00:00:00